LDLRAD1 and BNIP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		LDLRAD1	BNIP3
Description		low density lipoprotein receptor class A domain containing 1	BCL2 interacting protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Postsynaptic Density Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process		Autophagy Of Mitochondrion Response To Hypoxia Apoptotic Process Cell Death Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein-containing Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Negative Regulation Of Cell Death Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Mitochondrial Outer Membrane Permeabilization Granzyme-mediated Programmed Cell Death Signaling Pathway Toxin Transport Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Aerobic Respiration Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)
Interacting Genes		34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1	71 interacting genes: AGTR1 AMIGO1 ARL13B BCL2 BCL2L1 BCL2L2 BIK BNIP2 BNIP3L CD3E CD47 CLDN9 CLEC7A CLN8 CMTM5 CREB3 CREB3L1 EBAG9 EBP ELOVL4 ERGIC3 FAM209A FAM241B FATE1 FFAR2 FXYD6-FXYD2 GPR152 GPR37 GPR42 HIF1A HIVEP1 HPN HTR2B IFNGR2 JAGN1 KTN1 LDLRAD1 LMNA MALL MAP1LC3B MFSD14B MS4A3 NCBP1 OPA1 PLP2 PPTC7 REEP2 RHEB RNASEK RNF24 RPRM SCN3B SEC22A SEC23A SLC31A2 SLC35B1 SLC6A17 SMIM3 SPACA1 TGM2 TLCD4 TM4SF18 TMEM101 TMEM106C TMEM11 TMEM205 TMPRSS2 TMX2 TNMD TUBGCP2 ZDHHC15
Entrez ID		388633	664
HPRD ID		17372	04482
Ensembl ID		ENSG00000203985
Uniprot IDs		Q5T700	Q12983 Q6NVY4
PDB IDs			2J5D 2KA1 2KA2
Enriched GO Terms of Interacting Partners?
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