SMIM1 and RETREG3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMIM1	RETREG3
Description		small integral membrane protein 1 (Vel blood group)	reticulophagy regulator family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process		Positive Regulation Of Neuron Projection Development Reticulophagy
Pathways
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15	113 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARHGAP27 ARL6IP1 ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 C4orf3 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 IFITM3 JAGN1 KANSL1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 REEP6 RUNDC1 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 SPPL2C STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6
Entrez ID		388588	162427
HPRD ID			14108
Ensembl ID		ENSG00000235169	ENSG00000141699
Uniprot IDs		B2RUZ4 M4WDD3	K7EQI9 Q86VR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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