KRT16 and SEMA4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRT16	SEMA4C
Description		keratin 16	semaphorin 4C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome	Extracellular Space Integral Component Of Plasma Membrane Postsynaptic Density Synaptic Vesicle Membrane Postsynaptic Density Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Protein Binding Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier	Neural Crest Cell Migration Neural Tube Closure Axon Guidance Cell Migration In Hindbrain Cerebellum Development Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Muscle Cell Differentiation Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1	20 interacting genes: CYSRT1 DLG1 DLG2 DLG3 DLG4 GIPC1 HSF2BP KRT16 KRT27 KRT31 KRT34 KRT40 KRTAP6-3 NBPF19 NCDN NOTCH2NLA PNMA1 RCHY1 TRIM54 USHBP1
Entrez ID		3868	54910
HPRD ID		01018	07257
Ensembl ID		ENSG00000186832	ENSG00000168758
Uniprot IDs		P08779	Q9C0C4
PDB IDs			6N5Z
Enriched GO Terms of Interacting Partners?
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