KIT and PTPRO

  • Number of citations of the paper that reports this interaction (PubMedID 10397721)
  • 7
  • Data Source:
  • HPRD (in vivo)

KIT

PTPRO

Description KIT proto-oncogene, receptor tyrosine kinase protein tyrosine phosphatase receptor type O
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive function ( 22126837)
  • General cognitive ability ( 29844566)
  • Glomerular filtration rate (creatinine) ( 26831199)
  • Homeostasis model assessment of insulin resistance ( 33381925)
  • Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
  • Intelligence (MTAG) ( 29326435)
  • Metamizole-induced agranulocytosis or neutropenia ( 33138277)
  • Obstetric antiphospholipid syndrome ( 28424481)
  • Temporal pole volume ( 31530798)
Interacting Genes 93 interacting genes: ABL1 ABL2 BCAR3 BLK BLNK BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF1R CSF2RA CSF2RB DOK1 EPOR FES FGR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK HSH2D IL7R ILKAP INPP5D JAK2 JAK3 KDR KITLG LCK LYN MATK MPDZ NCK1 NCK2 PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCE1 PLCG1 PLCG2 PRKCA PRKCB PTK6 PTPN11 PTPN20 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SH2D1A SH2D1B SH2D2A SH2D3C SH3BP2 SHB SHC1 SHC2 SHC3 SHC4 SLA2 SOCS1 SOCS2 SOCS3 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B STYX SYK TEC TNS1 TNS2 TNS3 TXK VAV3 YES1 ZAP70 10 interacting genes: ACTG1 APP DPPA4 DPYSL4 KIT PIM1 SH3GL1 SH3GL3 UFL1 YWHAZ
Entrez ID 3815 5800
HPRD ID 01287 02784
Ensembl ID ENSG00000157404 ENSG00000151490
Uniprot IDs A0A0U2N547 P10721 A0A024RAS0 A0A024RAS9 Q16827
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2IUH 2VIF 3G0E 3G0F 4HVS 4K94 4K9E 4PGZ 4U0I 6GQJ 6GQK 6GQL 6GQM 6HH1 6ITT 6ITV 6KLA 6MOB 6XV9 6XVA 6XVB 2G59 2GJT
Enriched GO Terms of Interacting Partners?
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