ARF4 and APBA2

Number of citations of the paper that reports this interaction (PubMedID 12842896)
42

Data Source:
BioGRID (two hybrid)

		ARF4	APBA2
Description		ADP ribosylation factor 4	amyloid beta precursor protein binding family A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse	Cytoplasm Plasma Membrane Synaptic Vesicle Dendritic Spine
	Molecular Function	GTPase Activity Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding	Amyloid-beta Binding Protein Binding Identical Protein Binding
	Biological Process	Protein ADP-ribosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Cilium Assembly Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process	Chemical Synaptic Transmission Nervous System Development Protein Transport
Pathways		VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Neurexins and neuroligins
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Response to mTOR inhibitor (rapamycin) ( 24009623) SAPHO syndrome ( 33816493) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Temperament ( 22832960)
Interacting Genes		16 interacting genes: ADRB2 APBA1 APBA2 APBA3 COPS3 EGFR HNRNPD IKBKG ITIH1 PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA SUMO2	15 interacting genes: APP ARF3 ARF4 CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAGEB6 MAPK6 NECAB3 NRXN1 RELA STXBP1 USP20
Entrez ID		378	321
HPRD ID		03107	04090
Ensembl ID		ENSG00000168374	ENSG00000034053
Uniprot IDs		P18085	Q59G28 Q99767
PDB IDs		1Z6X
Enriched GO Terms of Interacting Partners?
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