VWC2 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VWC2	CAMLG
Description		von Willebrand factor C domain containing 2	calcium modulating ligand
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Interstitial Matrix Extracellular Space AMPA Glutamate Receptor Complex Synapse	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane GET Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation	B Cell Homeostasis Defense Response Signal Transduction Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			Cyclosporine
Diseases
GWAS		Age at first birth ( 34211149) Blood protein levels ( 30072576 29875488) Body mass index ( 28892062 25673413) Lung cancer in never smokers ( 28604730) Neurological blood protein biomarker levels ( 31320639) Post bronchodilator FEV1/FVC ratio ( 26634245) Pursuit maintenance gain ( 29064472) Serum thyroid-stimulating hormone levels ( 25436638)	Height ( 18391951)
Interacting Genes		57 interacting genes: ABHD15 ADAMTSL4 ATPAF2 CAMLG CATSPER1 CNNM3 CRY2 CYSRT1 ENKD1 FAM90A1 FBXW5 FUCA2 GET3 GNE HAPLN2 HOXA1 HPCA HPCAL1 KANK2 KPRP KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 LCE1A LCE1C LCE1F LCE2C LCE2D LCE3A LCE3D LCE3E LCE4A NTM OTX1 PFKFB1 POU4F2 PRPF31 SCNM1 SGTB SHFL SPRY1 TRAPPC14 UBQLN1 UBQLN2 VASN YY1 ZNF319 ZNF417 ZNF490 ZNF497 ZNF587 ZNF696 ZNF774 ZNF837	22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB STT3B TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		375567	819
HPRD ID		18271	03073
Ensembl ID		ENSG00000188730	ENSG00000164615
Uniprot IDs		Q2TAL6	P49069
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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