HDDC3 and EXOC5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		HDDC3	EXOC5
Description		HD domain containing 3	exocyst complex component 5
Image			No pdb structure
GO Annotations	Cellular Component		Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Metal Ion Binding	Protein Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process		Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport Protein Localization To Plasma Membrane Epithelial Cell Apoptotic Process Non-motile Cilium Assembly
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		15 interacting genes: AKAP9 APP CCDC172 CCHCR1 CEP57L1 EXOC5 GKAP1 GOLGA8EP GOLGA8F KIF7 MAGEA4 MSTO1 NMI TNIP1 TPM3	46 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 GNB1 HDDC3 HGS ICA1 IFT57 KIAA0586 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		374659	10640
HPRD ID		14635	07258
Ensembl ID		ENSG00000184508	ENSG00000070367
Uniprot IDs		Q8N4P3	O00471
PDB IDs		3NR1 5VXA
Enriched GO Terms of Interacting Partners?
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