KCNA5 and KCNA2

Number of citations of the paper that reports this interaction (PubMedID 12815189)
53

Data Source:
HPRD (in vivo)

		KCNA5	KCNA2
Description		potassium voltage-gated channel subfamily A member 5	potassium voltage-gated channel subfamily A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Cell Surface Intercalated Disc Integral Component Of Membrane Z Disc Potassium Channel Complex Membrane Raft Intracellular Canaliculus Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Integral Component Of Presynaptic Membrane
	Molecular Function	Signaling Receptor Binding Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Protein Kinase Binding Alpha-actinin Binding Voltage-gated Potassium Channel Activity Involved In Bundle Of His Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In SA Node Cell Action Potential Repolarization Scaffold Protein Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Kinesin Binding
	Biological Process	Response To Hypoxia Potassium Ion Transport Notch Signaling Pathway Response To Mechanical Stimulus Response To Organic Substance Regulation Of Vasoconstriction Regulation Of Membrane Potential Response To Hydrogen Peroxide Regulation Of Potassium Ion Transport Regulation Of Insulin Secretion Protein Homooligomerization Negative Regulation Of Cytosolic Calcium Ion Concentration Potassium Ion Homeostasis Response To Hyperoxia Membrane Hyperpolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Potassium Ion Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Bundle Of His Cell Action Potential Membrane Repolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Myoblast Proliferation	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Protein Homooligomerization Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Vernakalant Dalfampridine Isavuconazole	Enflurane Promethazine Miconazole Dalfampridine
Diseases
GWAS		Longevity ( 30294719)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		11 interacting genes: ACTN2 DLG1 DLG4 ERBIN KCNA2 PTPRE SNTA1 SRC TMEM107 TNK2 UBE2I	16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA
Entrez ID		3741	3737
HPRD ID		08888	01443
Ensembl ID		ENSG00000130037	ENSG00000177301
Uniprot IDs		P22460	P16389
PDB IDs
Enriched GO Terms of Interacting Partners?
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