CD82 and HLA-DMB

Number of citations of the paper that reports this interaction (PubMedID 9759843)
53

Data Source:
HPRD (in vivo)

		CD82	HLA-DMB
Description		CD82 molecule	major histocompatibility complex, class II, DM beta
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding MHC Class II Protein Complex Binding
	Biological Process		Adaptive Immune Response Immunoglobulin Production Involved In Immunoglobulin-mediated Immune Response MHC Class II Protein Complex Assembly Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Pathways			MHC class II antigen presentation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Cadmium levels ( 26025379) Hemostatic factors and hematological phenotypes ( 22443383) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Male-pattern baldness ( 27182965) Mean reticulocyte volume ( 32888494) Plasma parathyroid hormone levels ( 30134803) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Dermatomyositis ( 27153935) Lung cancer ( 28604730) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		27 interacting genes: BDKRB2 CANX CD19 CD4 CD63 CHRM5 CREB3 EGFR ERBB2 ERBB3 FFAR2 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 KLRC1 LRP1 NUP88 PTGFRN SMIM3 VANGL1	11 interacting genes: CD63 CD74 CD82 CUL3 DPM2 HLA-DMA HLA-DOB HLA-DRA MDM2 PSEN2 TEAD1
Entrez ID		3732	3109
HPRD ID		09004	00831
Ensembl ID		ENSG00000085117	ENSG00000242574
Uniprot IDs		P27701	A0A1V0E3P2 P28068
PDB IDs			1HDM 2BC4 4FQX 4GBX 4I0P
Enriched GO Terms of Interacting Partners?
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