JUN and CREB5

  • Number of citations of the paper that reports this interaction (PubMedID 8440710)
  • 28
  • Data Source:
  • HPRD (in vitro)

JUN

CREB5

Description Jun proto-oncogene, AP-1 transcription factor subunit cAMP responsive element binding protein 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 31417091)
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728)
  • Anxiety in major depressive disorder ( 24047446)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
  • Atrial fibrillation ( 30061737 29892015)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Blond vs. brown/black hair color ( 30531825)
  • Breast cancer ( 29059683)
  • Cataracts ( 34127677)
  • Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
  • Crohn's disease ( 23128233)
  • Diabetic retinopathy ( 21441570)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Ferritin levels ( 33491795)
  • Granulocyte count ( 27863252)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Hand grip strength ( 29691431)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 29403010 32888494 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Pulse pressure ( 27841878 30578418)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Smoking behaviour (cigarettes smoked per day) ( 31217584)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • TPE interval (resting) ( 32386560)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White blood cell count ( 29403010 32888494 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 189 interacting genes: ABL1 AKAP5 APLP2 APP AR ARRB1 ATF1 ATF2 ATF3 ATF4 BATF BATF2 BBS7 BCL3 BCL6 BLM BRCA1 CASP9 CCND1 CEBPE CEBPG CLINT1 COP1 COPS5 CREB3 CREB5 CREBBP CSNK2A1 DAB1 DACH1 DDIT3 DDX21 DHX9 DNMT3L EDF1 EGR1 ELF3 ELOF1 EN1 EP300 EPAS1 ERG ESR1 ETS1 ETS2 ETV1 ETV4 EWSR1 FBXW7 FOS FOSB FOSL1 FOSL2 GART GATA2 GOPC GPR18 GSK3B GTF2B GTF2E2 GTF2F1 GTF2F2 HCFC1 HDAC3 HDAC9 HDGF HHEX HIF1A HMGA1 HNRNPM HOXA9 HOXC8 HSP90AA1 HSPA8 IKBKB IRAK1 ISCU ITCH ITPK1 JDP2 KLF5 KMT2C KPNA2 M6PR MACF1 MAF MAFB MAP2K4 MAP2K7 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK5 MAPRE3 MBD3 MDM2 MOK MTA1 MYBBP1A MYOD1 NACA NAT14 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NEDD4 NELFB NFE2L1 NFE2L2 NFYA NFYC NR3C1 NR5A1 NRIP1 NTRK3 PACS1 PHOX2A PIAS1 PIAS2 PIN1 PML POU1F1 PPARG PPP3CB PPP4C PRKD1 PRKDC PRRC2A RB1 RBM39 RELA RNF187 ROR1 RPL18A RPS6KA2 RUNX1 RUNX2 SKI SMAD2 SMAD3 SMAD4 SMARCD1 SMARCD3 SNAPC5 SNIP1 SNRK SOX10 SOX8 SP1 SPI1 SPIB STAT1 STAT3 STAT4 STRN4 SUMO1 SUMO2 SUMO3 SUMO4 TACSTD2 TAF1 TAF4 TBP TCF20 TCF4 TDG TGIF1 TOP1 TOP2A TP53 TPM1 TPM2 TRAF2 TRIP4 TSC22D3 TSG101 UBB UBC UBE2I USP6 VAV1 VDR ZBTB7C 132 interacting genes: ADAMTSL4 AJUBA AKAP8L ALPP ANAPC11 ATF2 BATF3 CDPF1 CERCAM CIB4 CNFN COL8A1 CYP21A2 CYSRT1 EFEMP2 FBLN1 FHL3 FOS FOSB FOSL1 FOSL2 FRS3 FST HOXA1 HSD3B7 ID3 IGFBP6 INTS11 JDP2 JUN KIFC3 KPRP KRT15 KRT31 KRT40 KRT83 KRT85 KRT86 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP19-3 KRTAP19-5 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1C LCE2A LCE2C LCE4A LCE5A LGALS13 LITAF LMX1B MDFI MGAT5B MLLT6 MMADHC MTUS2 NADSYN1 NBPF19 NOTCH2NLA PCSK5 PLA2G10 PRDM14 PRR22 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS20 RIMBP3 RNF144B RNF208 SIVA1 SNAPC5 SPATA12 SPOP SPOPL SPRED1 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D TP53BP1 TRAF2 TRIM23 TRIM27 TRIM42 TRIP6 TSGA10 TSPAN4 TSR2 UFSP1 UNKL WWOX ZMAT5 ZNF330
Entrez ID 3725 9586
HPRD ID 01302 09896
Ensembl ID ENSG00000177606 ENSG00000146592
Uniprot IDs P05412 Q02930
PDB IDs 1A02 1FOS 1JNM 1JUN 1S9K 1T2K 5FV8 5T01 6Y3V
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?