IRF2 and PRKACA

  • Number of citations of the paper that reports this interaction (PubMedID 9213219)
  • 4
  • Data Source:
  • BioGRID (enzymatic study)

IRF2

PRKACA

Description interferon regulatory factor 2 protein kinase cAMP-activated catalytic subunit alpha
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute kidney injury in critical illness ( 27576016)
  • Adverse response to drug ( 30420678)
  • Chronic lymphocytic leukemia ( 28165464)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lewy body disease ( 25188341)
  • Night sleep phenotypes ( 27126917)
  • Nonsyndromic cleft lip ( 31609978)
  • Type 1 diabetes ( 34012112)
Interacting Genes 24 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFE2L2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1 TRIM55 TRIM63 219 interacting genes: AANAT ABCA1 ACLY ADCY5 ADD1 ADD2 AKAP1 AKAP14 AKAP8L AKIP1 ANXA7 APC APOBEC3G ARFGEF3 ASIC1 ASIC3 ATF1 ATP2B1 AURKA AVPI1 BAD BCL2 BFAR BRAF CACNA1C CACNB2 CACNG2 CAD CALD1 CAMKK2 CCDC88A CCND1 CD46 CDK16 CDKN1A CETN1 CFTR CIITA CLDN3 CLTC CREB1 CREM CRK CSK CUL5 CYP3A4 DMTN DNAJC5 DOCK1 DRD1 DSP EEF2K EGFR ELL ERBB3 ESR1 ETV1 FBXW11 FOS FXYD1 GABRB3 GABRR1 GAD1 GAD2 GFAP GJA5 GJB1 GLI1 GMFB GNA13 GNMT GP1BB GRIA1 GRIA4 GRK2 GSK3A GSK3B GUSB GYS1 HAND1 HAND2 HDAC1 HDAC8 HIF1A HMGCR HMGN1 HMGN2 HNF4A HNRNPD HSP90AA1 HSPA4 HSPD1 IFNAR1 IQGAP1 IRF2 ITCH ITGA2B ITGA4 ITPKA ITPKB ITPR1 ITPR2 KCNH2 KCNJ12 KCNQ1 KDELR1 KLF1 KLHL3 LCK LCP1 LIPE LRP1 MAP2 MAP3K3 MAPT MBP MC4R MECP2 MEF2D MEP1B MGMT MIP NDRG1 NFKB1 NIN NOLC1 NOS1 NOXA1 NR3C1 NSFL1C NUP85 PARK7 PDC PDE3A PDE3B PDE4B PDE4D PDPK1 PFKFB1 PFKFB2 PHKA1 PHOX2A PKIA PKIB PLIN1 PLN POU2F1 PPP1R10 PPP1R17 PPP1R1B PPP1R8 PPP1R9B PRKAR1A PRKAR1B PRKCA PSEN1 PSMD11 PTBP1 PTPN12 PTPN13 PTPN7 PTPRR RAB8A RAF1 RALBP1 RANBP9 RANGAP1 RAP1A RAP1B RAP1GAP RASGRF1 RASGRP3 RELA RFX1 RGS10 RGS13 RGS14 RHOA RRAD RSBN1 RYR1 RYR2 SI SIK1 SIK3 SLC2A2 SLC4A4 SLC9A3R2 SNAP25 SNAPIN SNPH SPTBN1 SRC STK11 STMN1 STMN2 STUB1 SYN1 SYN2 TCF4 TH THOP1 TNP1 TNP2 TPH1 TPM4 TRIM55 TRIM63 TRIP10 UBE3A UHRF1 USP20 UTRN VASP VIM VTN WT1 YWHAZ ZNF208
Entrez ID 3660 5566
HPRD ID 00962 03382
Ensembl ID ENSG00000168310 ENSG00000072062
Uniprot IDs P14316 A0A024R7J0 A8K8B9 P17612
PDB IDs 2GU8 3AGL 3AGM 3AMA 3AMB 3L9L 3L9M 3L9N 3MVJ 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M 3POO 3VQH 4AE6 4AE9 4UJ1 4UJ2 4UJ9 4UJA 4UJB 4WB5 4WB6 4WB7 4WB8 5BX6 5BX7 5IZF 5IZJ 5J5X 5N23 5UZK 6BYR 6BYS 6C0U 6FRX 6NO7 6QJ7 6WJF 6WJG
Enriched GO Terms of Interacting Partners?
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