INHA and INHBA

Number of citations of the paper that reports this interaction (PubMedID 11134153)
17

Data Source:
HPRD (in vitro)

		INHA	INHBA
Description		inhibin subunit alpha	inhibin subunit beta A
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Extracellular Region Extracellular Space Cytoplasm Inhibin-betaglycan-ActRII Complex Neuronal Cell Body Inhibin A Complex Inhibin B Complex	Extracellular Region Extracellular Space Activin A Complex Inhibin A Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Inhibin Binding Protein-containing Complex Binding	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Peptide Hormone Binding Inhibin Binding Identical Protein Binding Protein-containing Complex Binding Type II Activin Receptor Binding
	Biological Process	Skeletal System Development Ovarian Follicle Development Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Erythrocyte Differentiation Negative Regulation Of Interferon-gamma Production Regulation Of Cell Population Proliferation Negative Regulation Of Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of B Cell Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Regulation Of Cell Cycle SMAD Protein Signal Transduction	G1/S Transition Of Mitotic Cell Cycle Ovarian Follicle Development Hair Follicle Development Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II Defense Response Cell Surface Receptor Signaling Pathway Cell-cell Signaling Nervous System Development Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Xenobiotic Stimulus Response To Wounding Positive Regulation Of Gene Expression Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Striatal Medium Spiny Neuron Differentiation Cell Differentiation Erythrocyte Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Interferon-gamma Production Activin Receptor Signaling Pathway Endodermal Cell Differentiation Negative Regulation Of Phosphorylation Odontogenesis Hemoglobin Biosynthetic Process Progesterone Secretion Negative Regulation Of B Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Mesodermal Cell Differentiation Regulation Of Cell Cycle Roof Of Mouth Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Eyelid Development In Camera-type Eye Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Cholesterol GABAergic Neuron Differentiation Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Glycoprotein hormones	Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin
Drugs
Diseases
GWAS			Asthma ( 29273806) Cortisol levels (saliva) ( 28843169) Menarche (age at onset) ( 27182965 21102462 25231870) Parent of origin effect on language impairment (paternal) ( 24571439) Pit-and-Fissure caries ( 23470693)
Interacting Genes		5 interacting genes: FST INHBA INHBB SIAH1 TGFBR3	15 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B CD86 CHRDL2 ENG FST FSTL3 IGFBP7 INHA INHBB INHBC RALA TGFBR3
Entrez ID		3623	3624
HPRD ID		00933	00929
Ensembl ID		ENSG00000123999	ENSG00000122641
Uniprot IDs		P05111	A4D1W7 P08476
PDB IDs			1NYS 1NYU 1S4Y 2ARP 2ARV 2B0U 2P6A 3B4V 4MID 5HLY 5HLZ 6Y6N 6Y6O
Enriched GO Terms of Interacting Partners?
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