ING1 and SAP30

Number of citations of the paper that reports this interaction (PubMedID 11784859)
80

Data Source:
HPRD (in vitro, in vivo)

		ING1	SAP30
Description		inhibitor of growth family member 1	Sin3A associated protein 30
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GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	Protein Binding Methylated Histone Binding Metal Ion Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Import Into Nucleus Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Skeletal Muscle Cell Differentiation Modulation By Host Of Symbiont Transcription
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	27 interacting genes: BRMS1 BRMS1L CIR1 CYTOR GABBR2 H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		3621	8819
HPRD ID		03337	04540
Ensembl ID		ENSG00000153487	ENSG00000164105
Uniprot IDs		A0A0C4DFW2 Q9UK53	O75446
PDB IDs		2QIC	2KDP
Enriched GO Terms of Interacting Partners?
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