IMPA2 and IMPA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, biochemical, two hybrid)

		IMPA2	IMPA1
Description		inositol monophosphatase 2	inositol monophosphatase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol
	Molecular Function	Protein Binding Inositol Monophosphate 1-phosphatase Activity Protein Homodimerization Activity Metal Ion Binding Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity	Magnesium Ion Binding Protein Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process Inositol Phosphate Dephosphorylation	Inositol Metabolic Process Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process Inositol Phosphate Dephosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Synthesis of IP2, IP, and Ins in the cytosol
Drugs		Lithium cation Lithium citrate Lithium succinate Lithium carbonate	Lithium cation L-Myo-Inositol-1-Phosphate Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Hemoglobin ( 32888494) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Stroke ( 17434096)	Ovarian cancer ( 23535730)
Interacting Genes		6 interacting genes: CCT6A HERPUD1 IMPA1 SLC44A3 TNFRSF14 UBA3	4 interacting genes: CALB1 IMPA2 NXF1 S100B
Entrez ID		3613	3612
HPRD ID		09329	03641
Ensembl ID		ENSG00000141401	ENSG00000133731
Uniprot IDs		O14732	A0A024R830 A0A140VJL8 P29218
PDB IDs		2CZH 2CZI 2CZK 2DDK 2FVZ	1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4 6GIU 6GJ0 6ZK0
Enriched GO Terms of Interacting Partners?
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