IGHG4 and BAG5

		IGHG4	BAG5
Description		immunoglobulin heavy constant gamma 4 (G4m marker)	BAG cochaperone 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane Immunoglobulin Complex, Circulating Extracellular Exosome Blood Microparticle	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	Antigen Binding Immunoglobulin Receptor Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Phagocytosis, Recognition Phagocytosis, Engulfment Complement Activation, Classical Pathway Defense Response To Bacterium Innate Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)
Interacting Genes		1 interacting genes: BAG5	25 interacting genes: ANXA3 ATP5MJ BANP CDCA7L CIRBP CREBBP DES EFEMP1 FAM118B GOLGA6A IGHG4 JMJD6 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SIVA1 SNCA STUB1 THAP1 TP53 TRIM27 VCP
Entrez ID		3503	9529
HPRD ID		11757	04862
Ensembl ID		ENSG00000211892	ENSG00000166170
Uniprot IDs			A0A024R6M6 Q9UL15
PDB IDs			2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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