IFNGR2 and INSIG2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

IFNGR2

INSIG2

Description interferon gamma receptor 2 insulin induced gene 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Cholesterol, total ( 24097068)
  • Depression in response to interferon-based therapy in chronic hepatitis C ( 27723809)
  • Heel bone mineral density ( 30598549 28869591)
  • LDL cholesterol ( 24097068 30275531)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 32154731 33339817)
  • Lumbar spine bone mineral density ( 22504420)
  • Monobrow ( 27182965)
  • Mosquito bite size ( 28199695)
  • Total cholesterol levels ( 30275531)
Interacting Genes 46 interacting genes: ADIPOQ ANXA5 BNIP3 BRICD5 BTNL8 CAMK2D CCT8 CD302 CLDN19 CLEC7A CXCL9 DNAJA3 EMP3 ENTPD3 ERMP1 GIMAP5 GRIK1 HCRTR1 HLCS IFNG IFNGR1 INSIG2 JAGN1 JAK2 NR3C1 PMP22 RPL37A RTP2 SEC22B SFT2D2 SFTPC SLC52A1 SMIM3 STRIT1 TMEM120B TMEM140 TMEM199 TMEM218 TMEM254 TMEM60 TMEM97 TRARG1 TREX1 TSPAN2 UNC50 ZDHHC24 47 interacting genes: ABHD4 AQP2 AQP6 ATP6V0B BIK CD40 CD79A CPLX4 CREB3L1 CYBC1 EBP FAM209A GJA8 GOLM1 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LAPTM5 LHFPL5 LMNA MMGT1 MUC1 NEMP1 PCK1 PRLR PSCA PSMA7 PSMB1 PSMC3 PSMC5 PVR RNF5 SCAP SCN3B SLC16A10 SREBF2 STIM1 TMEM14B TMEM237 TMEM45B TMEM52B TMX2 VCP VMA21
Entrez ID 3460 51141
HPRD ID 00956 16361
Ensembl ID ENSG00000159128 ENSG00000125629
Uniprot IDs A8K881 E7EUY1 P38484 A0A024RAI2 B4DQ23 Q9Y5U4
PDB IDs 5EH1 6E3K 6E3L 4J82 6M49
Enriched GO Terms of Interacting Partners?
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