APOC4 and NFU1

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

APOC4

NFU1

Description apolipoprotein C4 NFU1 iron-sulfur cluster scaffold
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Blood protein levels ( 29875488 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • HDL cholesterol levels ( 32203549)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193043 18193044 20864672 19060906)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Quantitative traits ( 19197348)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 25 interacting genes: APOE APOL2 BCL2L2 DIABLO GAD2 GSDMA IFI27 LETMD1 MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 UBQLN1 UBQLN2 VKORC1 23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID 346 27247
HPRD ID 02848 12163
Ensembl ID ENSG00000267467 ENSG00000169599
Uniprot IDs P55056 Q9UMS0
PDB IDs 2LTM 2M5O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?