FAM174A and STX7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM174A	STX7
Description		family with sequence similarity 174 member A	syntaxin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process		Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Body shape index ( 34021172) Cutaneous leishmaniasis ( 32830257) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		36 interacting genes: ANKRD46 BET1 BNIP1 C14orf180 C4orf3 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB	53 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA LSMEM2 MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SNAP29 STX1A STX2 STX4 STX6 STX8 TM4SF19 TMEM205 TMEM241 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27
Entrez ID		345757	8417
HPRD ID		18260	04449
Ensembl ID		ENSG00000174132	ENSG00000079950
Uniprot IDs		Q8TBP5	O15400
PDB IDs
Enriched GO Terms of Interacting Partners?
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