HSD17B13 and UNC50

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD17B13	UNC50
Description		hydroxysteroid 17-beta dehydrogenase 13	unc-50 inner nuclear membrane RNA binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Nuclear Inner Membrane Integral Component Of Golgi Membrane
	Molecular Function	Molecular_function Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	RNA Binding Protein Binding
	Biological Process	Positive Regulation Of Lipid Biosynthetic Process	Protein Transport Protein Localization To Cell Surface
Pathways		Lipid particle organization
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Bulimia nervosa ( 23568457) Cirrhosis (alcohol related) ( 32853455) Cirrhosis (multi-trait analysis) ( 33310085) Liver enzyme levels (alanine transaminase) ( 22001757) Nonalcoholic steatohepatitis ( 32298765) Platelet count ( 22139419) Rosacea symptom severity ( 29771307) Triglyceride levels ( 31928498)	Diverticular disease ( 30177863)
Interacting Genes		118 interacting genes: ABHD16A ADGRE2 AGPAT3 AGPAT4 AGTRAP AIG1 ANKRD46 AOC3 APOA2 ARL6IP1 ATP6V0C BBC3 BRICD5 C3orf52 CACNG1 CALHM6 CCDC167 CDIPT CLDN10 CLDN19 CLDN4 CLDND2 CMTM5 CMTM7 CYB5R3 CYBC1 CYP4F2 DIABLO EBP ECPAS FATE1 FAXDC2 FETUB GJB2 GOLM1 GOSR2 GYPB HSD3B7 IGFBP5 INSIG2 ITGAM JAGN1 LPCAT2 LRAT MARCHF5 MFSD5 MGLL MIEF2 MMP14 MOSPD3 MS4A1 NAPB NAT8 NRM ORMDL3 PBX3 PLIN3 PLN PLP2 PNLIPRP1 PTPN9 RABAC1 REEP6 RHOU RPRM RUSF1 SACM1L SCAMP5 SCARF1 SCD SEC22B SERP1 SFT2D2 SFXN1 SFXN2 SFXN3 SLC25A46 SLC30A3 SLC35B4 SLC35E4 SMIM1 SNORC SPG21 ST6GAL2 STRIT1 STX5 STX7 TBRG4 TF THSD7A TIMM23 TIMMDC1 TMEM100 TMEM120A TMEM140 TMEM14C TMEM167B TMEM19 TMEM203 TMEM222 TMEM229B TMEM243 TMEM255B TMEM31 TMEM42 TMEM60 TMEM86B TMEM97 TMX2 TPRG1 TREX1 UBXN8 UNC50 VAMP2 VAPA VAPB YIPF2 YIPF4	33 interacting genes: AQP6 CLEC10A CLRN1 CREB3 DARS2 EBP ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FITM2 GPR152 GPX8 HSD17B11 HSD17B13 IFNGR2 KCNJ6 LMNA MFF MFSD14B MGST3 MTIF3 MUC1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 TMED8 TMEM14B TMEM167B TMEM234
Entrez ID		345275	25972
HPRD ID		18023	18259
Ensembl ID		ENSG00000170509	ENSG00000115446
Uniprot IDs		Q7Z5P4	A0A0S2Z612 J3KQ47 Q53HI1
PDB IDs
Enriched GO Terms of Interacting Partners?
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