RTP2 and ELOVL6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RTP2	ELOVL6
Description		receptor transporter protein 2	ELOVL fatty acid elongase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongase Complex Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Olfactory Receptor Binding	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Olfactory Signaling Pathway	Activation of gene expression by SREBF (SREBP) Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)	Attention deficit hyperactivity disorder ( 20732626) Benign prostatic hyperplasia ( 30988330) Depressive symptoms x dependent stressful life events interaction (1df test) ( 30718454) Liver enzyme levels (alkaline phosphatase) ( 33972514) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748)
Interacting Genes		72 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MFSD5 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SEC11C SGPL1 SLC10A6 SLC14A1 SLC34A2 SLC39A9 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21	3 interacting genes: HMOX1 LCP2 RTP2
Entrez ID		344892	79071
HPRD ID		12371	13269
Ensembl ID		ENSG00000198471	ENSG00000170522
Uniprot IDs		Q5QGT7	A1LV06 Q9H5J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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