IFIT1 and IFIT2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IFIT1	IFIT2
Description		interferon induced protein with tetratricopeptide repeats 1	interferon induced protein with tetratricopeptide repeats 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Host Cell	Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Response To Virus Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Protein Binding Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Defense Response To Virus Negative Regulation Of Helicase Activity Defense Response To Virus Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA Antiviral Innate Immune Response	Apoptotic Mitochondrial Changes Response To Virus Negative Regulation Of Protein Binding Cellular Response To Interferon-alpha Positive Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Blood protein levels ( 29875488)
Interacting Genes		4 interacting genes: EIF3E IFIT2 IFIT3 IFIT5	8 interacting genes: IFIT1 IFIT3 LMNA MEOX2 NUTM1 RBPMS2 WWOX WWP2
Entrez ID		3434	3433
HPRD ID		00983	00913
Ensembl ID		ENSG00000185745	ENSG00000119922
Uniprot IDs		P09914	P09913 Q05DN2
PDB IDs		4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K	4G1T
Enriched GO Terms of Interacting Partners?
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