RSPO2 and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RSPO2	KRTAP10-6
Description		R-spondin 2	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface	Cytosol Keratin Filament
	Molecular Function	Signaling Receptor Binding Protein Binding Heparin Binding	Protein Binding
	Biological Process	Osteoblast Differentiation Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Bone Mineralization Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Limb Development Lung Growth Epithelial Tube Branching Involved In Lung Morphogenesis Trachea Cartilage Morphogenesis Dopaminergic Neuron Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Regulation of FZD by ubiquitination	Keratinization
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) BMI x environmental factors (excluding physical activity) interaction ( 33654129) Brain morphology (MOSTest) ( 32665545) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Intake of total sugars ( 31005972) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		19 interacting genes: CATSPER1 CYSRT1 HOXA1 JMJD6 KRTAP10-1 KRTAP10-4 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP12-3 LGR4 LGR5 PLEKHF2 RNF43 SLC39A7 SUV39H1 ZNF330 ZNF837 ZNRF3	73 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-5 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-9 LCE1E LCE1F LCE2C LCE2D LCE3B LCE3E LCE4A MFSD3 MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		340419	386674
HPRD ID		17536	11192
Ensembl ID		ENSG00000147655	ENSG00000188155
Uniprot IDs		B3KVP3 Q6UXX9	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?
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