IHO1 and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		IHO1	FKBP6
Description		interactor of HORMAD1 1	FKBP prolyl isomerase family member 6 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Synaptonemal Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle
Pathways			Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS			Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B C1orf109 CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	37 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 PPP1R32 RAB11FIP2 RNF4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		339834	8468
HPRD ID		14172	05326
Ensembl ID		ENSG00000173421	ENSG00000077800
Uniprot IDs		B4DZP6 Q8IYA8	A0A3B3IST2 O75344
PDB IDs			3B7X
Enriched GO Terms of Interacting Partners?
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