CLEC4G and PKLR

Number of citations of the paper that reports this interaction (PubMedID 18624398)
18

Data Source:
BioGRID (two hybrid)

		CLEC4G	PKLR
Description		C-type lectin domain family 4 member G	pyruvate kinase L/R
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Polysaccharide Binding Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding	Magnesium Ion Binding Pyruvate Kinase Activity Protein Binding ATP Binding Kinase Activity Potassium Ion Binding
	Biological Process	Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of T Cell Proliferation Viral Entry Into Host Cell Positive Regulation Of Viral Life Cycle	Response To Hypoxia Glycolytic Process ATP Biosynthetic Process Response To Nutrient Response To Heat Response To Glucose Response To Lithium Ion Cellular Response To Insulin Stimulus Response To ATP Pyruvate Biosynthetic Process Response To CAMP Cellular Response To Epinephrine Stimulus
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Pyruvic acid 2-Phosphoglycolic Acid beta-D-fructofuranose 1,6-bisphosphate
Diseases
GWAS		Blood protein levels ( 28240269) Post bronchodilator FEV1 ( 26634245)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 24777453) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Major depressive disorder ( 29317602) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 23263486)
Interacting Genes		26 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 WBP2	5 interacting genes: CLEC4G CPNE7 MUC1 MYOC PCNA
Entrez ID		339390	5313
HPRD ID		16721	11841
Ensembl ID		ENSG00000182566	ENSG00000143627
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P30613
PDB IDs			2VGB 2VGF 2VGG 2VGI 4IMA 4IP7 6NN4 6NN5 6NN7 6NN8
Enriched GO Terms of Interacting Partners?
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