APOBEC1 and CELF2

Number of citations of the paper that reports this interaction (PubMedID 11577082)
39

Data Source:
HPRD (in vivo, in vitro)

		APOBEC1	CELF2
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 1	CUGBP Elav-like family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle Flemming Body Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding Ribonucleoprotein Complex Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Pre-mRNA Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Response To Xenobiotic Stimulus Cytidine Deamination Response To Zinc Ion Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Response To Ethanol Regulation Of Catalytic Activity Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of DNA Methylation-dependent Heterochromatin Assembly Positive Regulation Of MRNA Modification	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection RNA Processing Regulation Of Heart Contraction
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs		Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)	Activity variability during wake ( 33075057) Adult body size ( 32376654) Adventurousness ( 30643258) Adverse response to drug ( 30420678) Age at first sexual intercourse ( 34211149) Allergic rhinitis ( 30013184) Asthma ( 34103634 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Basal cell carcinoma ( 33549134) Body size at age 10 ( 32376654) Breastfeeding duration ( 25475840) Chronic kidney disease ( 31015462) Cognitive function in longevity ( 33607172) General risk tolerance (MTAG) ( 30643258) Glaucoma (primary open-angle) ( 33627673) Glycemic traits (pleiotropy) ( 31021400) Liver enzyme levels (alanine transaminase) ( 24124411) Liver enzyme levels (aspartate transaminase) ( 24124411) Mean platelet volume ( 32888494) Motion sickness ( 25628336) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653) Response to lamotrigine in genetic generalized epilepsy ( 32308125) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		17 interacting genes: A1CF APOBEC2 BAG4 CACNA1I CDK6 CELF2 DNAJB11 DND1 HNRNPF HNRNPK KPNA2 KRTAP19-5 KRTAP6-1 KRTAP6-2 NOTO SYNCRIP UFSP2	21 interacting genes: A1CF APOBEC1 APP ELAVL1 MIR140 MIR155 MIR18B MIR199A1 MIR19A MIR19B1 MIR205 MIR21 MIR29C MIR34B MIR363 MIR7-1 MIR9-2 MIRLET7I PCBP1 PTGS2 TRAF3
Entrez ID		339	10659
HPRD ID		02531	03964
Ensembl ID		ENSG00000111701	ENSG00000048740
Uniprot IDs		P41238	A0A0J9YX66 A0A0J9YXJ0 A0A1B0GU44 A0A1B0GUN8 B4DDE7 B4DIB6 B4DT00 B4DZ01 E9PC62 O95319
PDB IDs		6X91	2MY7 2MY8 4LJM 4LMZ 4TLQ 5M8I
Enriched GO Terms of Interacting Partners?
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