ICAM3 and RPL18

		ICAM3	RPL18
Description		intercellular adhesion molecule 3	ribosomal protein L18
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Nucleus Nucleolus Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Polysomal Ribosome
	Molecular Function	Signaling Receptor Binding Integrin Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Phagocytosis Cell Adhesion Cell-cell Adhesion	Cytoplasmic Translation Translation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Bipolar disorder ( 21926972) Elevated serum carcinoembryonic antigen levels ( 24941225) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		29 interacting genes: APP BRICD5 C3 CALR CD209 CLDN19 CLDN4 CLEC4M EDDM3B EPOR EZR GCC2 ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ PRLR RFX2 RPL18 SEC22A SFTPC SMCO4 SMIM1 TNFRSF1B TSPO USF2 ZBTB16	6 interacting genes: CDKN1A DUX4 FANCA FANCC ICAM3 IL7R
Entrez ID		3385	6141
HPRD ID		00889	16046
Ensembl ID		ENSG00000076662	ENSG00000063177
Uniprot IDs		A0A024R7C1 K7ERN2 P32942	A0A024QZD1 Q07020
PDB IDs		1T0P	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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