ICA1 and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ICA1	RAB2A
Description		islet cell autoantigen 1	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Secretory Granule Membrane Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Membrane Curvature Sensor Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Neurotransmitter Transport Regulation Of Insulin Secretion Regulation Of Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Intraocular pressure ( 23836780) Metabolite levels (Pyroglutamine) ( 23934736) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 28714469)	Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		8 interacting genes: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B SHANK3 TSC1	30 interacting genes: ASPH BLZF1 CBFB CCDC125 CFL2 CPA4 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 RP1 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		3382	5862
HPRD ID		00971	01539
Ensembl ID		ENSG00000003147	ENSG00000104388
Uniprot IDs		A0A024RA29 Q05084	A0A024R7V6 P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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