KRTAP8-1 and FOXP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP8-1	FOXP3
Description		keratin associated protein 8-1	forkhead box P3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Metal Ion Binding NF-kappaB Binding NFAT Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II B Cell Homeostasis Negative Regulation Of Cytokine Production Myeloid Cell Homeostasis CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment T Cell Mediated Immunity Tolerance Induction To Self Antigen Regulation Of T Cell Anergy Positive Regulation Of T Cell Anergy Negative Regulation Of Chronic Inflammatory Response Negative Regulation Of T Cell Cytokine Production Positive Regulation Of Peripheral T Cell Tolerance Induction Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Response To Radiation Response To Virus Gene Expression Establishment Of Endothelial Blood-brain Barrier Negative Regulation Of Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-4 Production Negative Regulation Of CREB Transcription Factor Activity Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Histone Acetylation Negative Regulation Of Histone Acetylation T Cell Activation Negative Regulation Of T Cell Proliferation T Cell Homeostasis Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Isotype Switching To IgE Isotypes Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Defense Response To Virus Negative Regulation Of Immune Response T Cell Receptor Signaling Pathway Response To Rapamycin Negative Regulation Of T-helper 17 Cell Differentiation
Pathways		Keratinization	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) RUNX1 regulates transcription of genes involved in WNT signaling
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Vitiligo ( 27723757)
Interacting Genes		78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 C20orf85 CAMK2A CCDC17 CCNK CDA CERCAM CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MFSD13A MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PPP1R32 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34	18 interacting genes: EP300 FOSB IKZF4 KAT8 KRTAP3-3 KRTAP6-2 KRTAP8-1 MDM2 NFAT5 NFATC2 NLK PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS RUNX1
Entrez ID		337879	50943
HPRD ID		11221	02242
Ensembl ID		ENSG00000183640	ENSG00000049768
Uniprot IDs		Q8IUC2	B7ZLG1 Q9BZS1
PDB IDs			3QRF 4WK8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?