UBAC2 and GET4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		UBAC2	GET4
Description		UBA domain containing 2	guided entry of tail-anchored proteins factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex
	Molecular Function	Protein Binding	Protein Binding Chaperone Binding
	Biological Process	Wnt Signaling Pathway Protein Localization To Endoplasmic Reticulum Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (childhood onset) ( 31036433 30929738) Basal cell carcinoma ( 21700618) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cuneus cortex volume ( 31530798) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908) Medication use (adrenergics, inhalants) ( 31015401) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 33536424) Tinnitus ( 33742053)	PR interval ( 32439900)
Interacting Genes		5 interacting genes: CALCOCO2 GET4 LMO7 MIR182 UBC	30 interacting genes: AKT1 ATP5PD BAG6 C1orf109 CAPNS1 CDKN1A CEP126 DNAAF5 DUSP21 EEF1G ENKD1 FBN1 FLYWCH2 GET3 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2
Entrez ID		337867	51608
HPRD ID		11429	12909
Ensembl ID		ENSG00000134882	ENSG00000239857
Uniprot IDs		A0A024RE02 A8K2S7 Q8NBM4	Q7L5D6
PDB IDs			6AU8
Enriched GO Terms of Interacting Partners?
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