TNC and SMOC2

Number of citations of the paper that reports this interaction (PubMedID 21349332)
16

Data Source:
BioGRID (pull down)

		TNC	SMOC2
Description		tenascin C	SPARC related modular calcium binding 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Interstitial Matrix Extracellular Space Endoplasmic Reticulum Lumen Focal Adhesion Membrane Collagen-containing Extracellular Matrix Perisynaptic Extracellular Matrix	Basement Membrane Extracellular Space Cell Periphery
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Syndecan Binding	Calcium Ion Binding Protein Binding Heparin Binding Extracellular Matrix Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Negative Regulation Of Cell Adhesion Neuromuscular Junction Development Positive Regulation Of Cell Population Proliferation Response To Wounding Response To Mechanical Stimulus Positive Regulation Of Gene Expression Peripheral Nervous System Axon Regeneration Wound Healing Odontogenesis Of Dentin-containing Tooth Response To Ethanol Bud Outgrowth Involved In Lung Branching Mesenchymal-epithelial Cell Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Cellular Response To Retinoic Acid Cellular Response To Vitamin D Response To Fibroblast Growth Factor Cellular Response To Prostaglandin D Stimulus	Positive Regulation Of Endothelial Cell Migration Extracellular Matrix Organization Positive Regulation Of Vascular Wound Healing Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis
Pathways		Integrin cell surface interactions Syndecan interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 29875488 28240269) Developmental language disorder (syntactic complexity) ( 27016271) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Osteoarthritis (hip) ( 30374069) Response to bupropion and depression ( 27622933)	Circulating leptin levels in high cardiovascular risk ( 31766143) Copper levels ( 26025379) Corneal astigmatism ( 30306274) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Loneliness ( 27629369) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Pulse pressure ( 30224653 27841878) Thyroid stimulating hormone levels ( 32769997) Vitiligo ( 19890347) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: ANXA2 ASTN2 CNTN1 EGFR FN1 ITGA5 ITGB1 MBD1 NCAN POLE3 PTPRB RAB14 SMOC1 SMOC2 SPARC TRIM32	3 interacting genes: FBXO7 KRTAP5-1 TNC
Entrez ID		3371	64094
HPRD ID		01756	06244
Ensembl ID		ENSG00000041982	ENSG00000112562
Uniprot IDs		B4E1W8 J3QSU6 P24821 Q4LE33	Q9H3U7
PDB IDs		1TEN 2RB8 2RBL 5R5T 5R5U 5R5V 5R5W 5R5X 5R5Y 5R5Z 5R60 5R61 5R62 5R63 6BRB 6QNV
Enriched GO Terms of Interacting Partners?
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