HSD3B1 and SLC16A13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD3B1	SLC16A13
Description		hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	solute carrier family 16 member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Smooth Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Intercellular Bridge	Golgi Membrane Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	3-keto Sterol Reductase Activity 3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Steroid Delta-isomerase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 5alpha-androstane-3beta,17beta-diol Dehydrogenase Activity Cholesterol Dehydrogenase Activity	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Symporter Activity
	Biological Process	Steroid Biosynthetic Process Androgen Biosynthetic Process Estrogen Biosynthetic Process C21-steroid Hormone Metabolic Process Hippocampus Development Response To Corticosterone	Monocarboxylic Acid Transport Transmembrane Transport
Pathways		Androgen biosynthesis Mineralocorticoid biosynthesis Glucocorticoid biosynthesis
Drugs		NADH Trilostane Androstenedione Hydrocortisone aceponate Hydrocortisone acetate Hydrocortisone butyrate Hydrocortisone cypionate Hydrocortisone phosphate Hydrocortisone probutate Hydrocortisone valerate
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)	Type 2 diabetes ( 26818947 23945395 24390345)
Interacting Genes		3 interacting genes: AQP6 SLC16A13 TMEM14B	19 interacting genes: AQP6 ATP13A1 BSG CCNDBP1 CD79A CREB3L1 FAM210B FXYD6-FXYD2 GJA8 HSD3B1 JPH1 PGRMC2 PTPN9 SHISAL1 SLC10A1 SYNDIG1 TMEM14B TMEM160 TMEM50B
Entrez ID		3283	201232
HPRD ID		04920	18054
Ensembl ID		ENSG00000203857	ENSG00000174327
Uniprot IDs		P14060	Q7RTY0
PDB IDs
Enriched GO Terms of Interacting Partners?
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