APEX1 and TCF21

  • Number of citations of the paper that reports this interaction (PubMedID 20211142)
  • 361
  • Data Source:
  • BioGRID (two hybrid)

APEX1

TCF21

Description apurinic/apyrimidinic endodeoxyribonuclease 1 transcription factor 21
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood pressure traits (multi-trait analysis) ( 28498854)
  • Blood urea nitrogen levels ( 31152163)
  • Coronary artery disease ( 32469254 29212778 24262325 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary artery disease or ischemic stroke ( 24262325)
  • Coronary artery disease or large artery stroke ( 24262325)
  • Coronary heart disease ( 22751097 21378990)
  • Diastolic blood pressure ( 28498854)
  • Haemorrhoidal disease ( 33888516)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • PR interval ( 32439900)
  • Pulse pressure ( 28498854)
  • Systolic blood pressure ( 28498854)
Interacting Genes 44 interacting genes: ANP32A ANP32C APP CDC42 CSNK2A1 DCTN1 EP300 FBXO7 FEN1 GZMA GZMK HDAC1 HIF1A HMGA1 HMGA2 HMGB2 HNRNPL HOXC13 HSPA1A LINC01554 MCL1 MDM2 MUTYH NFE2L2 NME1 NUDT3 NXF2 PCNA POLB POLR3D SET SRPK1 SRPK2 TCF21 TERF1 TERF2 TERF2IP TP53 TXN UBE2I UBR3 XRCC1 XRCC5 XRCC6 10 interacting genes: APEX1 APLP1 GTF3C5 HOXB6 KLF15 LMO4 MYOD1 SDCBP TCF12 TCF3
Entrez ID 328 6943
HPRD ID 00136 04493
Ensembl ID ENSG00000100823 ENSG00000118526
Uniprot IDs P27695 Q5TZP7 O43680
PDB IDs 1BIX 1CQG 1CQH 1DE8 1DE9 1DEW 1E9N 1HD7 2ISI 2O3H 3U8U 4IEM 4LND 4QH9 4QHD 4QHE 5CFG 5DFF 5DFH 5DFI 5DFJ 5DG0 5WN0 5WN1 5WN2 5WN3 5WN4 5WN5 6BOQ 6BOR 6BOS 6BOT 6BOU 6BOV 6BOW 6MK3 6MKK 6MKM 6MKO 6P93 6P94 6W0Q 6W2P 6W3L 6W3N 6W3Q 6W3U 6W43 6W4I 6W4T
Enriched GO Terms of Interacting Partners?
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