APEH and UBA5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APEH	UBA5
Description		acylaminoacyl-peptide hydrolase	ubiquitin like modifier activating enzyme 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Nuclear Membrane Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Serine-type Endopeptidase Activity Protein Binding Omega Peptidase Activity Identical Protein Binding	Protein Binding ATP Binding Zinc Ion Binding Protein Homodimerization Activity UFM1 Activating Enzyme Activity
	Biological Process	Translational Termination Proteolysis Amyloid-beta Metabolic Process	Erythrocyte Differentiation Megakaryocyte Differentiation Protein Modification By Small Protein Conjugation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Neutrophil degranulation Eukaryotic Translation Termination	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Feeling tense ( 29500382) Feeling worry ( 29500382) Household income ( 31844048) Inflammatory bowel disease ( 28067908) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 21297633)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: IST1 LGALS8 SHBG TMEM62 UBA5	8 interacting genes: APEH GABARAPL2 OGT PKD1P1 UBE2D2 UBE2L3 UFC1 UFM1
Entrez ID		327	79876
HPRD ID		00034	15598
Ensembl ID		ENSG00000164062	ENSG00000081307
Uniprot IDs		P13798	Q9GZZ9
PDB IDs			3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C
Enriched GO Terms of Interacting Partners?
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