AGFG1 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
6

Data Source:
BioGRID (fluorescent resonance energy transfer)

		AGFG1	DNAJC5
Description		ArfGAP with FG repeats 1	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Nuclear Pore Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	MRNA Export From Nucleus Spermatogenesis Cell Differentiation Regulation Of Catalytic Activity	Exocytosis Synaptic Vesicle Exocytosis Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neutrophil degranulation GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Asthma ( 31959851) Mild influenza (H1N1) infection ( 26379185)	Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		16 interacting genes: APC APP CUL3 DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 OGT PKIA POLE2 RNF216 TRIM54 VAMP7 XPO1	49 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CD2 CFTR CGB5 CLCN3 ERC1 FAS FCHO1 GRM8 HBA2 KHDC4 LIN7A LIN7C NECAP1 NRXN3 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		3267	80331
HPRD ID		02918	08539
Ensembl ID		ENSG00000173744	ENSG00000101152
Uniprot IDs		A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594	Q6AHX3 Q9H3Z4
PDB IDs		2D9L 2OLM 2VX8	2N04 2N05
Enriched GO Terms of Interacting Partners?
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