HOXA3 and PWP1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXA3	PWP1
Description		homeobox A3	PWP1 homolog, endonuclein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Chromosome Nucleolus Golgi Apparatus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding HMG Box Domain Binding	H4K20me3 Modified Histone Binding
	Biological Process	Angiogenesis Blood Vessel Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Anterior/posterior Pattern Specification Specification Of Animal Organ Position Gene Expression Glossopharyngeal Nerve Morphogenesis Thyroid Gland Development Thymus Development Animal Organ Formation Embryonic Skeletal System Morphogenesis Cartilage Development Parathyroid Gland Development	Transcription, DNA-templated RRNA Processing Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Histone H4-K20 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Stem Cell Differentiation
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body shape index ( 34021172) Chronic venous disease ( 28374850) Diastolic blood pressure ( 27618448) Hypertension ( 27618448 30487518) Lymphocyte counts ( 32888494) Mean arterial pressure ( 27618448) Monocyte count ( 32888494 27863252) Pulse pressure ( 30487518) Systolic blood pressure ( 28135244 27618448 30487518) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)	Acne (severe) ( 24927181)
Interacting Genes		10 interacting genes: ALX4 ARPC3 POT1 PWP1 RCHY1 SEC23B SOX10 TERF1 TINF2 ZDHHC17	9 interacting genes: APP CKAP4 CUL4B DAPK1 DCAF1 HOXA3 NFYA OGT SMURF1
Entrez ID		3200	11137
HPRD ID		00842	11464
Ensembl ID		ENSG00000105997	ENSG00000136045
Uniprot IDs		A0A024RA33 A4D182 B3KPN8 O43365	A0A024RBH5 B4DJV5 Q13610
PDB IDs
Enriched GO Terms of Interacting Partners?
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