HMOX2 and NDUFS2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		HMOX2	NDUFS2
Description		heme oxygenase 2	NADH:ubiquinone oxidoreductase core subunit S2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Nucleoplasm Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Oxygen Sensor Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Quinone Binding NAD Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Response To Hypoxia Heme Oxidation Response To Oxidative Stress Heme Catabolic Process Iron Ion Homeostasis	Mitochondrial Electron Transport, NADH To Ubiquinone Response To Oxidative Stress Neurogenesis Mitochondrial Respiratory Chain Complex I Assembly Gliogenesis Mitochondrial ATP Synthesis Coupled Electron Transport Neural Precursor Cell Proliferation Cellular Response To Oxygen Levels
Pathways		Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1	Respiratory electron transport Complex I biogenesis
Drugs		NADH Stannsoporfin	NADH
Diseases
GWAS		Erectile dysfunction ( 30583798)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 31361310) Asthma ( 31361310 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Granulocyte percentage of myeloid white cells ( 27863252)
Interacting Genes		66 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LRIF1 MARK3 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	5 interacting genes: APP CENPU EGR2 HMOX2 TNFRSF14
Entrez ID		3163	4720
HPRD ID		00783	04285
Ensembl ID		ENSG00000103415	ENSG00000158864
Uniprot IDs		A0A087WT44 B3KSE0 P30519	B7Z792 O75306
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA	5XTB 5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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