HMGCS2 and ERO1B

		HMGCS2	ERO1B
Description		3-hydroxy-3-methylglutaryl-CoA synthase 2	endoplasmic reticulum oxidoreductase 1 beta
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Hydroxymethylglutaryl-CoA Synthase Activity Identical Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Thiol Oxidase Activity Unfolded Protein Binding FAD Binding
	Biological Process	Acetyl-CoA Metabolic Process Cholesterol Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process, Mevalonate Pathway Ketone Body Biosynthetic Process	Protein Folding Protein Folding In Endoplasmic Reticulum
Pathways		PPARA activates gene expression Synthesis of Ketone Bodies	Insulin processing
Drugs			1-Ethyl-Pyrrolidine-2,5-Dione Flavin adenine dinucleotide
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Macular telangiectasia type 2 ( 33654266) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: APP ERO1B FBXO7 HSD17B10 PTPN22	11 interacting genes: ACTL6A BRCA1 CNRIP1 ERP44 GNG4 HMGCS2 OGT P4HB PARVA PYGM TARBP1
Entrez ID		3158	56605
HPRD ID		02580	13279
Ensembl ID		ENSG00000134240	ENSG00000086619
Uniprot IDs		A0A140VJL2 P54868	Q86YB8
PDB IDs		2WYA
Enriched GO Terms of Interacting Partners?
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