HMGB2 and SNAPIN

Number of citations of the paper that reports this interaction (PubMedID 31694235)
4

Data Source:
BioGRID (two hybrid)

		HMGB2	SNAPIN
Description		high mobility group box 2	SNAP associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Condensed Chromosome Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Protein-containing Complex Perinuclear Region Of Cytoplasm	Golgi Membrane Acrosomal Vesicle Manchette Lysosomal Membrane Synaptic Vesicle Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm BORC Complex Axon Cytoplasm
	Molecular Function	Four-way Junction DNA Binding Transcription Cis-regulatory Region Binding Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Transcription Factor Binding DNA Binding, Bending Protein Domain Specific Binding Chemoattractant Activity Non-sequence-specific DNA Binding, Bending RAGE Receptor Binding Supercoiled DNA Binding	SNARE Binding Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Inflammatory Response To Antigenic Stimulus DNA Topological Change Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Nucleus Differentiation Male Gonad Development Negative Regulation Of Gene Expression Positive Regulation Of Nuclease Activity DNA Geometric Change Response To Lipopolysaccharide Positive Regulation Of Interferon-beta Production V(D)J Recombination Positive Regulation Of DNA Binding Innate Immune Response Positive Regulation Of Innate Immune Response Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Steroid Hormone Regulation Of Neurogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Cell Chemotaxis Cellular Response To Lipopolysaccharide Regulation Of Stem Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Intracellular Protein Transport Lysosome Organization Lysosomal Lumen Acidification Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Cellular Protein-containing Complex Localization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Protein Maturation Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Apoptosis induced DNA fragmentation	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: APEX1 APP AR ARCN1 C1QBP CACTIN CHAF1A COMMD1 CREBBP CSNK1A1 EIF1 FBXO7 FLNA GZMA GZMK H3-3A HACD3 HDLBP HMGA1 LZTS1 MIEN1 MYL6 NAP1L1 NCBP3 NEXN NOP53 NR3C1 PGR PKNOX1 POU2F1 POU2F2 POU3F1 POU5F1 PRKDC RAG1 RPS28 SAMM50 SET SNAPIN TERT TP53 TSNAX U2AF1 UHRF2 ZNF428 ZNF622 ZNF668	104 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYSF EBAG9 EEF1G ELP1 ENO3 ENTHD1 EXOC1 EXOC7 FAM114A1 FSD2 GPRASP1 HAP1 HMGB2 IKBIP IMMT INSYN1 KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 KRT27 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ
Entrez ID		3148	23557
HPRD ID		01229	06111
Ensembl ID		ENSG00000164104	ENSG00000143553
Uniprot IDs		P26583	O95295
PDB IDs
Enriched GO Terms of Interacting Partners?
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