HLA-DRB4 and ASMTL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		HLA-DRB4	ASMTL
Description		major histocompatibility complex, class II, DR beta 4	acetylserotonin O-methyltransferase like
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Cytosol
	Molecular Function	MHC Class II Protein Complex Binding	Molecular_function Protein Binding O-methyltransferase Activity NADH Pyrophosphatase Activity DTTP Diphosphatase Activity UTP Diphosphatase Activity Nucleoside-triphosphate Diphosphatase Activity
	Biological Process	Adaptive Immune Response Immunoglobulin Production Involved In Immunoglobulin-mediated Immune Response Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Activation	Biological_process Nucleotide Metabolic Process Methylation
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling
Drugs		1D09C3 Coccidioides immitis spherule
Diseases
GWAS
Interacting Genes		3 interacting genes: ASMTL CTAG1B MAGEA6	10 interacting genes: APP GORASP2 HLA-DRB4 KRT31 KRT34 KRT40 PNMA1 REL TDO2 ZNF655
Entrez ID		3126	8623
HPRD ID		09986	02156
Ensembl ID			ENSG00000169093
Uniprot IDs		P13762 X5D2U9	B3KM43 O95671
PDB IDs			2P5X
Enriched GO Terms of Interacting Partners?
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