HIF1A and ARNTL

  • Number of citations of the paper that reports this interaction (PubMedID 9576906)
  • 234
  • Data Source:
  • HPRD (in vivo, two hybrid)

HIF1A

ARNTL

Description hypoxia inducible factor 1 subunit alpha aryl hydrocarbon receptor nuclear translocator like
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Body mass index ( 25673413)
  • C-reactive protein levels ( 30388399)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Caffeine consumption from tea ( 33287642)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronotype ( 30696823)
  • Cooked vegetable consumption ( 32066663)
  • Coronary artery disease ( 32469254 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Depression in multiple sclerosis (pre-diagnosis) ( 33296963)
  • Diastolic blood pressure ( 27841878 27618448 30487518)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Face memory ( 31596458)
  • Feeling guilty ( 29500382)
  • Feeling miserable ( 29500382)
  • Fish- and plant-related diet ( 32066663)
  • General risk tolerance (MTAG) ( 30643258)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Mean arterial pressure ( 30487518)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Menarche (age at onset) ( 27182965 21102462 25231870)
  • Metabolic syndrome ( 31589552)
  • Neurociticism ( 29500382)
  • PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
  • Psoriasis ( 30921485)
  • Red blood cell count ( 32888494)
  • Schizophrenia ( 23358160)
  • Sociability score ( 34054130)
  • Systolic blood pressure ( 31928498)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Tea consumption ( 31046077)
  • Triglyceride levels ( 32203549 32154731 31928498 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Worry too long after an embarrassing experience ( 29500382 34054130)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes 127 interacting genes: AKT1 APEX1 AR ARNT ARNT2 ARNTL ATM AURKA BNIP3 CASR CCND2 CDC34 CDK4 CDK6 CDKN2A CDKN2B CITED2 COPS5 CREB3L1 CREBBP CSNK1D CSNK2A1 CTNNB1 DAP3 E2F7 EAF2 EGLN1 EGLN2 EGLN3 EIF5A2 EP300 EPHA2 EPO ESRRA ESRRB ESRRG ETV4 F12 FBXO8 FGFR4 FZR1 GATA3 GLIS2 HDAC1 HDAC2 HDAC3 HDAC5 HIF1A-AS2 HIF1AN HIF3A HNF4A HSP90AA1 IKBKG ISG15 JUN KPNA1 KPNA3 KPNA4 KPNA5 KPNA6 LATS2 LINC01139 LRRK2 MAFG MAFK MAP2K3 MAP2K5 MAPK1 MAPK3 MAX MCL1 MCM7 MDM2 MTA1 MYC NAA10 NAA11 NBN NCOA1 NCOA2 NDN NEDD8 NF2 NQO1 NR4A1 OS9 PER1 PGK1 PKM PLD1 PLD2 PLK3 PRKACA PSMA7 PTBP1 PTK6 RACGAP1 RACK1 RB1 RORA RUNX2 RWDD3 SAT1 SEPTIN9 SIRT2 SMAD3 SNHG11 SP1 SSX4 STAT3 STK11 STUB1 SUCO SUMO1 TEAD2 TP53 TSGA10 UBE2D1 UBE2I USP19 USP20 USP28 USP7 VEGFA VHL VHLL ZC3H12A 25 interacting genes: AHR AZIN1 BHLHE40 CLOCK CRY1 CSNK1E DELEC1 DHTKD1 EP300 EPAS1 HIF1A HLF HSP90AA1 KAT2B NPAS2 NPAS4 PER3 RARA RHOA RHOU RXRA SIRT1 TRAPPC12 UBE2I ZMYND12
Entrez ID 3091 406
HPRD ID 04517 03973
Ensembl ID ENSG00000100644 ENSG00000133794
Uniprot IDs D0VY79 Q16665 A0A140VKD3 A0A669KBF4 B2RCL8 O00327
PDB IDs 1D7G 1H2K 1H2L 1H2M 1L3E 1L8C 1LM8 1LQB 2ILM 3HQR 3HQU 4AJY 4H6J 5JWP 5L9B 5L9V 5LA9 5LAS 6GFX 6GMR 6YW3 4H10
Enriched GO Terms of Interacting Partners?
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