EHD3 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EHD3	ARL6IP1
Description		EH domain containing 3	ADP ribosylation factor like GTPase 6 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Focal Adhesion Endosome Membrane Ciliary Pocket Membrane Endocytic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding	Protein Binding Identical Protein Binding
	Biological Process	Receptor Recycling Endocytosis Protein Transport Endosomal Transport Endocytic Recycling Early Endosome To Golgi Transport Protein Homooligomerization Regulation Of Cardiac Muscle Contraction Cilium Assembly Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Golgi To Lysosome Transport Positive Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Golgi Organization Regulation Of Cardiac Conduction	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Estradiol levels ( 22675492) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Mean platelet volume ( 22139419 24026423 19820697 32888494 27863252) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Platelet count ( 22139419 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)	Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ARL6IP1 EHD1 MICALL1 SNAP29	77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		30845	23204
HPRD ID		16170	09641
Ensembl ID		ENSG00000013016	ENSG00000170540
Uniprot IDs		Q9NZN3	A0A024QYV7 Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?
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