CD209 and CEACAM1

Number of citations of the paper that reports this interaction (PubMedID 16246332)
32

Data Source:
HPRD (in vivo)

		CD209	CEACAM1
Description		CD209 molecule	CEA cell adhesion molecule 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Basal Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Cell Junction Transport Vesicle Membrane Microvillus Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding	Molecular_function Actin Binding Protein Binding Calmodulin Binding Bile Acid Transmembrane Transporter Activity Kinase Binding Protein Phosphatase Binding Filamin Binding Identical Protein Binding Protein Homodimerization Activity Protein Dimerization Activity Protein Tyrosine Kinase Binding
	Biological Process	Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion Positive Regulation Of Viral Life Cycle	Angiogenesis Regulation Of Cell Growth Blood Vessel Development Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Negative Regulation Of Protein Kinase Activity Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Bile Acid And Bile Salt Transport Cell Migration Regulation Of Cell Migration Negative Regulation Of Granulocyte Differentiation Negative Regulation Of Interleukin-1 Production Cellular Response To Insulin Stimulus Common Myeloid Progenitor Cell Proliferation Insulin Receptor Internalization Granulocyte Colony-stimulating Factor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Vascular Permeability Negative Regulation Of Cytotoxic T Cell Degranulation Wound Healing, Spreading Of Cells Regulation Of Endothelial Cell Differentiation Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Lipid Biosynthetic Process Regulation Of Blood Vessel Remodeling Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Platelet Aggregation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Insulin Catabolic Process Regulation Of Homophilic Cell Adhesion Regulation Of Sprouting Angiogenesis Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Vasculogenesis
Pathways		CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs			Technetium Tc-99m arcitumomab
Diseases
GWAS		Blood protein levels ( 30072576 29875488)
Interacting Genes		9 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 IFT20 ITGAM TCEAL8 VAC14	19 interacting genes: ADRB2 ANXA2 APOE CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC
Entrez ID		30835	634
HPRD ID		05241	00191
Ensembl ID		ENSG00000090659	ENSG00000079385
Uniprot IDs		B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12	P13688 Q3KRG8
PDB IDs		1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV	2GK2 4QXW 4WHD 5DZL 6AW2 6GBG 6GBH 6V3P
Enriched GO Terms of Interacting Partners?
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