ADGRE2 and MARCHF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ADGRE2	MARCHF6
Description		adhesion G protein-coupled receptor E2	membrane associated ring-CH-type finger 6
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane	ER Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Enzyme Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding
	Biological Process	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis	Proteasomal Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Endoplasmic Reticulum Mannose Trimming
Pathways		Class B/2 (Secretin family receptors)	ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80	10 interacting genes: ADGRE2 BUD31 DIO2 DNAH5 MTNR1B RGS2 TRIO UBC UBE2D2 UBE2G1
Entrez ID		30817	10299
HPRD ID		07308	11095
Ensembl ID		ENSG00000127507	ENSG00000145495
Uniprot IDs		A0JNV7 Q9UHX3	O60337
PDB IDs		2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?
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