CFH and VDR

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CFH

VDR

Description complement factor H vitamin D receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23577725 32741009 23455636 23536807 20861866 21665990 15761122)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (MTAG) ( 32277175)
  • Aspartate aminotransferase levels ( 33547301)
  • Blood protein levels ( 29875488 28240269)
  • Chronic central serous retinopathy ( 30480742 30073298)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Complement C3 and C4 levels ( 23028341)
  • Complement C3 levels ( 33941608)
  • Complement factor H binding to malondialdehyde ( 32321835)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Early age-related macular degeneration ( 32843070)
  • Exudative age-related macular degeneration ( 25629512)
  • Fuchs's corneal dystrophy ( 28358029)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Matrix metalloproteinase-8 levels ( 29212897)
  • Meningococcal disease ( 20694013)
  • Neovascular age-related macular degeneration ( 28703135)
  • Nephropathy ( 21399633)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Rheumatic heart disease ( 34106200)
  • Serum C3d:C3 ratio (systemic complement activation) ( 29398083)
  • Sub-foveal choroidal thickness ( 29844195)
  • Systemic lupus erythematosus ( 28714469)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 16 interacting genes: ADM C3 CFHR1 CFI CRP DMP1 EP300 GRB2 ITGAM PTX3 SELL SMAD3 THBS1 VDR YTHDC1 ZBTB16 80 interacting genes: ACTN4 ACVR1 ANKRD11 BAG1 CCND3 CDCA7L CDK7 CFH CLASRP COPS2 CREBBP CSNK2A1 CXXC5 FGR FOS FOXO3 GABARAPL1 GABARAPL2 GNPAT GOLM2 GRIP1 GTF2B HMGN3 HR JUN KDM5A LCOR MAPK1 MAPK3 MED1 MED12 MED14 MED23 MEOX2 MMRN2 MYC NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NKD2 NLRP3 NR0B2 NR1H2 NRIP1 NSD1 NTAQ1 OTUD4 POLR2A POU1F1 POU2F1 PPARG PPP1CA PPP2CA PRCP PRKCSH PSMC5 RB1 RNF14 RPS6KC1 RUNX1 RUNX1T1 RXRA RXRB RXRG SIRT1 SMAD3 SNW1 SRC SRPK1 STAG1 STAT1 TAF11 TDG TRIM24 TRIP13 ZBTB16
Entrez ID 3075 7421
HPRD ID 00601 03463
Ensembl ID ENSG00000000971 ENSG00000111424
Uniprot IDs A0A024R962 A0A0D9SG88 P08603 F1D8P8 P11473
PDB IDs 1FHC 1HAQ 1HCC 1HFH 1HFI 1KOV 2BZM 2G7I 2IC4 2JGW 2JGX 2KMS 2QFG 2QFH 2RLP 2RLQ 2UWN 2V8E 2W80 2W81 2WII 2XQW 3GAU 3GAV 3GAW 3KXV 3KZJ 3OXU 3R62 3RJ3 3SW0 4AYD 4AYE 4AYI 4AYM 4B2R 4B2S 4J38 4K12 4ONT 4ZH1 5NBQ 5O32 5O35 5WTB 6ATG 1DB1 1IE8 1IE9 1KB2 1KB4 1KB6 1S0Z 1S19 1TXI 1YNW 2HAM 2HAR 2HAS 2HB7 2HB8 3A2I 3A2J 3A3Z 3A40 3A78 3AUQ 3AUR 3AX8 3AZ1 3AZ2 3AZ3 3B0T 3CS4 3CS6 3KPZ 3M7R 3OGT 3P8X 3TKC 3VHW 3W0A 3W0C 3W0Y 3WGP 3WWR 3X31 3X36 4G2I 4ITE 4ITF 5GT4 5V39 5YSY 5YT2
Enriched GO Terms of Interacting Partners?
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