HDC and GZMA

Number of citations of the paper that reports this interaction (PubMedID 19059912)
25

		HDC	GZMA
Description		histidine decarboxylase	granzyme A
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Immunological Synapse Extracellular Region Nucleus
	Molecular Function	Histidine Decarboxylase Activity Protein Binding Carboxy-lyase Activity Pyridoxal Phosphate Binding	Serine-type Endopeptidase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Histamine Biosynthetic Process Histidine Metabolic Process Histidine Catabolic Process Catecholamine Biosynthetic Process	Apoptotic Process Immune Response Response To Bacterium Cytolysis Negative Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of Oxidoreductase Activity Proteolysis Involved In Cellular Protein Catabolic Process Pyroptosis Granzyme-mediated Programmed Cell Death Signaling Pathway Cytotoxic T Cell Pyroptotic Process
Pathways		Histidine catabolism
Drugs		Pyridoxal phosphate Histidine
Diseases
GWAS		Basophil count ( 32888494) Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		2 interacting genes: DTX2 GZMA	19 interacting genes: ACTG1 APEX1 GOLGA2 H1-1 H2BC21 HDC HMGB2 HNRNPK HSP90AA1 HSPA4 LMNA LMNB1 NCL NDUFS3 NFIX PCP4 SET XRCC5 XRCC6
Entrez ID		3067	3001
HPRD ID		00817	00771
Ensembl ID		ENSG00000140287	ENSG00000145649
Uniprot IDs		P19113	P12544
PDB IDs		4E1O	1HF1 1OP8 1ORF
Enriched GO Terms of Interacting Partners?
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