HADHB and COX17

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		HADHB	COX17
Description		hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta	cytochrome c oxidase copper chaperone COX17
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Mitochondrial Nucleoid	Cytoplasm Mitochondrial Intermembrane Space
	Molecular Function	RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Acetyl-CoA C-acyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Acetyl-CoA C-myristoyltransferase Activity	Copper Ion Binding Protein Binding Copper Chaperone Activity Cuprous Ion Binding
	Biological Process	Fatty Acid Beta-oxidation	Generation Of Precursor Metabolites And Energy Copper Ion Transport Brain Development Heart Development Positive Regulation Of Cell Population Proliferation Mitochondrial Cytochrome C Oxidase Assembly Positive Regulation Of Cytochrome-c Oxidase Activity
Pathways		Acyl chain remodeling of CL Beta oxidation of myristoyl-CoA to lauroyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Mitochondrial protein import
Drugs
Diseases
GWAS			Tau burden ( 33426524)
Interacting Genes		16 interacting genes: ALK ANXA7 APP CDC42 CDKN1A CHCHD4 COX17 GRB7 HSD17B10 HSPB2 RCC1 SMN1 SUOX TIMM8B TK1 TNNI3K	12 interacting genes: COPS6 EEF1A1 ERG28 HADHB KATNAL1 KRTAP10-8 LRIF1 PPBP RB1 RBM48 TP53 UNC119
Entrez ID		3032	10063
HPRD ID		00887	05314
Ensembl ID		ENSG00000138029	ENSG00000138495
Uniprot IDs		F5GZQ3 P55084	Q14061
PDB IDs		5ZQZ 5ZRV 6DV2	2L0Y 2LGQ 2RN9 2RNB
Enriched GO Terms of Interacting Partners?
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