HADHA and ATXN2L

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		HADHA	ATXN2L
Description		hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha	ataxin 2 like
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Mitochondrial Nucleoid	Cytosol Cytoplasmic Stress Granule Membrane Nuclear Speck
	Molecular Function	Fatty-acyl-CoA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Acetyl-CoA C-acetyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Protein-containing Complex Binding NAD+ Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	Fatty Acid Beta-oxidation Response To Xenobiotic Stimulus Response To Insulin Cardiolipin Acyl-chain Remodeling	Stress Granule Assembly
Pathways		Acyl chain remodeling of CL Beta oxidation of myristoyl-CoA to lauroyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Drugs		NADH
Diseases
GWAS			Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever or eczema) ( 29679657) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 28552196 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Crohn's disease ( 28067908) Educational attainment ( 25201988 23722424) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Extremely high intelligence ( 29520040) Hand grip strength ( 29691431) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Left-handedness ( 32989287) Pediatric autoimmune diseases ( 26301688) Waist circumference ( 28552196) Weight ( 28552196)
Interacting Genes		9 interacting genes: ABCF2 ATXN2L CD74 HSD17B10 NCOA1 NR4A1 PIN1 PTEN YWHAQ	41 interacting genes: ATXN1 BOLL EPOR HADHA HOXA1 KRTAP12-4 MIR1-1 MIR10B MIR128-1 MIR128-2 MIR15B MIR16-2 MIR17 MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPL OGT
Entrez ID		3030	11273
HPRD ID		02934	06394
Ensembl ID		ENSG00000084754	ENSG00000168488
Uniprot IDs		E9KL44 P40939	H3BUF6 Q8WWM7
PDB IDs		5ZQZ 5ZRV 6DV2
Enriched GO Terms of Interacting Partners?
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