ERO1A and KLHDC2

		ERO1A	KLHDC2
Description		endoplasmic reticulum oxidoreductase 1 alpha	kelch domain containing 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nuclear Body Cul2-RING Ubiquitin Ligase Complex Nuclear Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding	Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Protein Folding Cellular Protein Modification Process Response To Oxidative Stress Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways		Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		15 interacting genes: APPBP2 DYNLT1 EBF1 ERP44 GPX7 GPX8 KLHDC2 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU	9 interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 SELENOK SELENOS STRN4 USP1
Entrez ID		30001	23588
HPRD ID		13278	08824
Ensembl ID		ENSG00000197930	ENSG00000165516
Uniprot IDs		Q96HE7	Q9Y2U9
PDB IDs		3AHQ 3AHR	6DO3 6DO4 6DO5
Enriched GO Terms of Interacting Partners?
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