CERS2 and SLC19A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CERS2	SLC19A2
Description		ceramide synthase 2	solute carrier family 19 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Protein Binding Folic Acid Transmembrane Transporter Activity Thiamine Transmembrane Transporter Activity
	Biological Process	Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process Negative Regulation Of Axon Regeneration Negative Regulation Of Schwann Cell Migration Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration	Folic Acid Transport Thiamine Transport Thiamine-containing Compound Metabolic Process Transmembrane Transport Thiamine Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis	Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Body mass index ( 26426971) Caffeine consumption from coffee or tea ( 33287642) Estimated glomerular filtration rate ( 31152163 31015462) Facial attractiveness (female raters) ( 30946739) Glycated hemoglobin levels ( 34059833 28898252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Reticulocyte fraction of red cells ( 27863252) Rhegmatogenous retinal detachment ( 23585552)	Plasma factor V levels in venous thrombosis ( 31271701) Venous thromboembolism ( 21980494)
Interacting Genes		14 interacting genes: ASGR1 ASGR2 ATP6V0C DRD2 HSP90AA1 IER3IP1 NFE2L2 PEX6 SLC19A2 SLC22A1 SLC39A1 TMBIM6 TNFSF4 YIF1A	3 interacting genes: CERS2 DEDD SC5D
Entrez ID		29956	10560
HPRD ID		06080	04897
Ensembl ID		ENSG00000143418	ENSG00000117479
Uniprot IDs		Q96G23	A0A024R8Y5 A0A024R928 O60779
PDB IDs
Enriched GO Terms of Interacting Partners?
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