DNMT3L and GTF3C5

Number of citations of the paper that reports this interaction (PubMedID 24952347)
14

Data Source:
BioGRID (pull down)

		DNMT3L	GTF3C5
Description		DNA methyltransferase 3 like	general transcription factor IIIC subunit 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	Protein Binding Enzyme Activator Activity Enzyme Binding Metal Ion Binding	DNA Binding Protein Binding
	Biological Process	DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Male Meiosis I Spermatogenesis DNA Methylation On Cytosine DNA Methylation Involved In Gamete Generation Negative Regulation Of Transcription, DNA-templated Stem Cell Differentiation Regulation Of Catalytic Activity Negative Regulation Of DNA Methylation Positive Regulation Of DNA Methylation	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		DNA methylation	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Sepsis (28-day mortality) ( 32592749)
Interacting Genes		78 interacting genes: - ASH2L ATF1 ATF2 ATF3 ATF4 BLZF1 CDX2 CREB1 CREBL2 CREM DDIT3 DLX4 DMTF1 DNMT3A DNMT3B DR1 E2F3 E2F5 E2F6 EGR1 EGR2 EGR4 ESR1 ESR2 ETS1 F2RL1 FOS FOSB FOSL1 FOSL2 GATA1 GMEB1 GSK3B GTF2H2 GTF2I GTF3C5 H2AC20 H2BC21 H3C14 H4C14 HAND1 HAND2 HDAC1 HNF4G HOXA5 HOXC11 ID1 JUN JUNB KLF12 LDB1 LHX2 MAFK MECP2 MED7 MEF2A MEF2D NFIL3 NFKB1 NR1H2 NR1I2 NR1I3 NR2E1 NR3C1 NR6A1 NUDT21 PDZD4 PHPT1 RELA RSL24D1 RXRA SMAD1 SMAD3 SMAD4 TLE5 TP53 YY1	16 interacting genes: BRF1 DNMT3L GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 KRTAP12-3 MDFI NOTCH2NLA OGT PTEN SRA1 TBP TCF21 TCF4
Entrez ID		29947	9328
HPRD ID		09417	16077
Ensembl ID		ENSG00000142182	ENSG00000148308
Uniprot IDs		Q9UJW3	H7BY84 Q9Y5Q8
PDB IDs		2PV0 2PVC 2QRV 4U7P 4U7T 5YX2 6BRR 6F57 6KDA 6KDB 6KDL 6KDP 6KDT 6U8P 6U8V 6U8W 6U8X 6U90 6U91 6W89 6W8B 6W8D 6W8J
Enriched GO Terms of Interacting Partners?
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